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WOUND HEALING AND ANTI-INFLAMMATORY EFFECT IN ANIMAL MODELS OF CALENDULA OFFICINALIS

January 20, 2014 by  
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Scientific research: Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil

Abstract
Calendula officinalis is an annual herb from Mediterranean origin which is popularly used in wound healing and as an anti-inflammatory agent. In this study, the ethanolic extract, the dichloromethane, and hexanic fractions of the flowers from plants growing in Brazil were produced. The angiogenic activity of the extract and fractions was evaluated through the chorioallantoic membrane and cutaneous wounds in rat models. The healing activity of the extract was evaluated by the same cutaneous wounds model through macroscopic, morphometric, histopathologic, and immunohistochemical analysis.

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The antibacterial activity of the extract and fractions was also evaluated. This experimental study revealed that C. officinalis presented anti-inflammatory and antibacterial activities as well as angiogenic and fibroplastic properties acting in a positive way on the inflammatory and proliferative phases of the healing process.

 

 

Yours In Great Health,
Sar Rooney BHSc., ND., DC., DASc., GDSc. (Hons) Zoology, MHATO, MATMS, MNHAA
Naturopathic Physician, Medical Herbalist & Dog Naturopath
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CITATION: Evidence-Based Complementary and Alternative MedicineVolume 2012 (2012), Article ID 375671, 7 pages, http://dx.doi.org/10.1155/2012/375671
Copyright © 2012 Leila Maria Leal Parente et al. http://www.hindawi.com/journals/ecam/2012/375671/abs/
FULL ARTICLE: http://www.hindawi.com/journals/ecam/2012/375671/
SOURCE: Open Access article courtesy of Hindawi – Creative Commons Attribution 3.0 Unported Licence

 

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Natural Animal Health for pets, specialising in natural health for dogs. Naturopathic dog therapy with a holistic approach to animal health may complement conventional vet treatments. We offer expert naturopathic advice for dogs from a qualified animal naturopath that specializes in natural dog health. We are based in South Australia's Adelaide Hills region but consult throughout Australia and internationally, with clients in South Australia, Queensland, Victoria, the ACT, NSW, the NT, Tasmania, Western Australia, New Zealand, the UK, the US and other countries throughout the world. While we specialise in dogs health problems and natural animal therapy we also treat people with naturopathic medicine and offer clinic services in natural health. Many clients have found natural animal therapy to be more effective or less invasive than conventional vet services. Our clients have a common interest in the health and wellbeing of their dog and are looking for natural preventative health programs and natural remedies for dogs such as herbal medicines and homeopathy that are often not offered by veterinary practices or veterinarian clinics in Australia and New Zealand. Canine natural pain relief and natural animal therapy for inflammation are common conditions that may benefit from naturopathic animal health treatments and holistic pet care.


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